Open access
Sep 2026
Antisense Oligonucleotide-Mediated XIST Knockdown Modulates Endogenous Pluripotency-Associated Transcription Factor Expression in Porcine Female Somatic Cells
Simple Summary Somatic cell reprogramming is an important technology for animal biotechnology, embryo engineering, and genetic improvement. However, the efficiency of reprogramming is limited by epigenetic barriers that restrict the activation of pluripotency-related genes. The long non-coding RNA XIST plays a central...
Xiao-Yu Chen, Xiao-Hong Chu, Jing Huang et al.
· Animals · 0 citations