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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Liang Zhang

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Aug 2026

Dual MYC and GSPT1 Protein Degrader for MYC-Driven Hematologic Malignancies.

Direct targeting of the oncoprotein MYC has not yet been successful. We here report a novel dual protein degrader, GT19630, which binds directly to MYC and G1 to S phase transition protein 1 (GSPT1). GT19630 disrupts a novel feedforward loop of MYC and GSPT1, where MYC promotes transcription of GSPT1, and GSPT1 senses...

Yuki Nishida, Valeria Impedovo, Edward Ayoub et al. · 0 citations

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