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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Liangyu Chen

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Aug 2026

FSCN1 promotes rheumatoid arthritis progression via inhibiting TRIM38-mediated ubiquitination of IGF2BP1 in fibroblast-like synoviocytes.

OBJECTIVE Fibroblast-like synoviocytes (FLS) in rheumatoid arthritis (RA) synovium acquire a unique aggressive phenotype and produce cytokines that perpetuate inflammation and proteases that contribute to cartilage destruction. Actin bundling protein Fascin-1 (FSCN1) is involved in FLS migration and invasion, but its r...

Liangyu Chen, Jun-Feng Wu, Tao Zhou et al. · 0 citations

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