Author

Lieve Temmerman

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Open access Oct 2026

Divergence Between Marker Expression and Phenotype During Human Corneal Endothelial Cell Expansion.

Purpose The purpose of this study was to compare whether conventional marker-based assessments adequately reflect phenotypic stability during serial passaging of two established culture protocols for primary human corneal endothelial cells (CEnCs). Methods Primary CEnCs were isolated from paired donor corneas from 25...

Filippo Bonelli, Tom S. Bailey, Iveta Dzivite et al. · Investigative Ophthalmology... · 0 citations

Open access Sep 2026

Atherosclerotic plaque fibroblasts derive from adventitial and medial Pdgfra-lineage-positive cells and predominantly maintain fibroblast identity.

AIMS Fibroblasts are mesenchymal cells in the healthy vascular adventitia. In atherosclerosis, single-cell sequencing datasets suggest fibroblasts are abundant in plaques. However, their identity, origin, and fate during plaque progression remain unclear, which we aim to unravel here. APPROACH AND RESULTS To robustly...

Guan-Liang Li, S. Asselberghs, Bai-Xue Yu et al. · Cardiovascular Research · 0 citations