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Lijuan Wang

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Open access Sep 2026

Adipose-derived microRNA-518a drives hepatic cholesterol dysregulation and hypertension-related vascular remodeling in metabolic dysfunction-associated steatohepatitis via the MST1-AMPK-SREBP2 axis.

INTRODUCTION Metabolic dysfunction-associated steatohepatitis (MASH) is characterized by disrupted hepatic lipid homeostasis and progressive liver injury, and frequently coexists with hypertension and systemic vascular remodeling, suggesting shared pathophysiological mechanisms. Although adipose tissue-derived microRNA...

Yu Xu, Si-Han Zhang, Kun Wang et al. · 0 citations

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