Open access
Aug 2026
Recognition of pathogenic bacteria by intestinal stem cells promotes adult Drosophila midgut regeneration
It is shown that adult Drosophila midgut ISCs recognise pathogenic bacteria through the peptidoglycan recognition proteins, PGRP-LC and PGRP-LE, and translate this into their proliferation by stimulating Imd-Mkk3-p38 signalling.
Bhavin Uttekar, Marie Srotyr, Sanket Sudam Ravale et al.
· PLoS Biology · 0 citations