Most metabolites showed biologically plausible patterns, correlating with specific pro- and antioxidant exposures and including metabolites previously implicated in oxidative stress-related processes, and inversely associated with CVD and T2D risk at baseline.
L. Goñi, Gonzalo Fernández-Duval, C. Razquín et al.· Metabolism: Clinical and Exp...· 0 citations
The results suggest that population-level associations of asthma with psychosis spectrum conditions could be due to shared molecular mechanisms involving fatty acid metabolism, ion channel activity, and iron homeostasis.
C. Dardani, J. W. Robinson, A. Havdahl et al.· Biological Psychiatry· 0 citations
In older Black adults, circulating inflammatory proteins were linked to cognition, reinforcing the role of systemic inflammation as a potential driver of neurodegeneration in this population.
Anat Yaskolka Meir, H. Adeola, S. Tasaki et al.· Brain : a journal of neurolo...· 0 citations
By analyzing associations between community-level factors and inflammation-related proteins, this study provides new molecular insights into how social context may relate to biological risk, identifies proteomic patterns that could inform the development of community-level interventions, and underscores the utility of...
Anat Yaskolka Meir, H. Adeola, S. Tasaki et al.· BMC Medicine· 0 citations
It is suggested that routinely measured clinical characteristics may help identify populations with greater expected blood pressure response to sodium reduction, and salt sensitivity varied across age, SBP, and body mass index strata.