Lin Chen

C-20 Diterpenoid Alkaloids with PD-L1 Inhibitory Activity from the Roots of Aconitum coreanum

Fifteen previously unreported diterpenoid alkaloids, named aconicorines A-O (1–15), and 13 known diterpenoid alkaloids (16–28) were isolated from the roots of Aconitum coreanum. Their structures and configurations were determined by comprehensive spectroscopic analysis including HRMS, NMR, and single-crystal X-ray di...