Poor prognosis of acute kidney injury superimposed on chronic kidney disease: potential mechanisms, risk factors and novel biomarkers
Acute kidney injury superimposed on chronic kidney disease (acute-on-chronic kidney injury, hereinafter referred to as AoCKI) is a common clinical syndrome with a generally poor prognosis compared to isolated acute kidney injury (AKI). Patients with AoCKI often face significantly heightened mortality, increased depende...