Lin Huang

CoCoBind: Consistency-Contrastive Multitask Learning for RNA–Ligand Interaction and Binding Site Prediction

CoBind is presented, a multitask deep learning framework that jointly predicts RNA–compound interactions and nucleotide-level binding-site probabilities within a unified architecture and provides complementary nucleotide-level binding-site localization, supporting a site-aware view of RNA–ligand recognition under distribution shift.