Lin Ji

Mitophagy–pyroptosis–macrophage polarization crosstalk in cardiovascular diseases: mechanistic insights and therapeutic potential

Cardiovascular disease (CVD) is one of the leading causes of global morbidity and mortality. Its development and progression are closely associated with mitochondrial dysfunction, sterile inflammation, and immunometabolic dysregulation. Mitophagy, a key mechanism of mitochondrial quality control, maintains mitochondria...