Open access
Sep 2026
Knockdown of SENP7 attenuates cognitive impairment in offspring mice induced by maternal sevoflurane anesthesia partially through cGAS/STING/IRF3-mediated pyroptosis
Exposure to sevoflurane (SEV) during pregnancy is associated with long-term cognitive impairment in offspring; however, the precise mechanisms remain unclear. This study aimed to investigate the role of Sentrin/SUMO-specific peptidase 7 (SENP7) and its downstream pathways in SEV-induced neurotoxicity. Preg...
Jin-Teng Du, Xue Ma, Ke-Qin Hua et al.
· Molecular Brain · 0 citations