Author

Lin-Ping Wu

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Aug 2026

Integrin β6-Targeted CAR-T Cells exhibit potent antitumor activity in β6-Positive pancreatic ductal adenocarcinoma and lung adenocarcinoma.

Pancreatic ductal adenocarcinoma (PDAC) and lung adenocarcinoma (LUAD) remain lethal malignancies with limited therapeutic options, highlighting an urgent need for more effective treatments. Integrin αvβ6 (ITGB6) is a receptor preferentially expressed in specific types of tumors, such as PDAC and LUAD, and represents a...

Ling-Chao Shi, L. Qin, Shu-Xin Sun et al. · Molecular Cancer Therapeutic... · 0 citations

Sep 2026

A Self-Assembling Janus Dendron-Modified Phthalocyanine Enables Deep Tumor-Targeted Therapy for Gastric Cancer Peritoneal Metastases.

Peritoneal metastasis is a leading cause of mortality in end-stage gastric cancer and remains poorly responsive to conventional chemotherapy. To address this unmet need, Janus dendron-modified phthalocyanines were developed as tumor-targeted photosensitizers for photodynamic therapy (PDT). A series of Janus dendron-mod...

Jian-Ping Guo, Shu-Jie Zhang, Zi-Jian Deng et al. · Advanced Healthcare Material... · 0 citations

Review Open access Aug 2026

Targeted delivery of mRNA to immune cells for in vivo cell therapy

The integration of rational material design, high-throughput screening, artificial intelligence, and interdisciplinary collaboration will be essential to advance next-generation targeted in vivo mRNA cell therapies toward clinical translation.

Danyang Wang, Yumin Li, Jinfeng Deng et al. · Drug Delivery · 0 citations