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Author

Lin-Wei Li

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Review Open access Sep 2026

NLRP3-mediated pyroptosis in cardiovascular disease: from molecular mechanisms to therapeutic targets

Globally, cardiovascular disease has consistently been the leading cause of death. Its pathogenesis is complex and involves interactions among multiple factors, with inflammatory mechanisms garnering increasing attention. Pyroptosis—pro-inflammatory programmed cell death—is categorized into classical, non-classical, an...

Qiu-Yu Xu, Wei Sun, Lin-Wei Li et al. · 0 citations
Review Open access Sep 2026

Targeting the secretory autophagy–extracellular vesicle interface: fate decisions and translational opportunities

Autophagy preserves cellular homeostasis through lysosomal degradation, but its machinery also participates in extracellular release. This creates a pharmacological problem: changing autophagy or extracellular vesicle (EV) output can alter intracellular disposal, inflammatory signaling and communication between cells i...

Lin-Lin Deng, Lin-Wei Li, Zhi-Jun Huang et al. · 0 citations

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