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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Lin Yin

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Sep 2026

A Self-Locking DNAzyme Platform for Highly Specific Sensing of Low-Abundance Single-Base Mutations

A self-locking DNAzyme (SLOD) biosensor that suppresses spontaneous activation through a thermodynamically stabilized intramolecular inactive conformation that establishes a low-background, single-base-discriminating, and modular DNAzyme biosensor platform for single-base mutation detection and clinically relevant nucl...

Yu-Zhao Wang, Lin Yin, Jing-Xi Liu et al. · 0 citations

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