Author

Lin Zheng

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Open access Jul 2026

SALL2 constrains TEAD4 by maintaining repressive chromatin to restrict trophectoderm identity

It is demonstrated that SALL2 knockdown in primed human pluripotent stem cells (hPSCs) triggers a trophectoderm (TE)-like phenotype, characterized by palisade-like morphology and the up-regulation of TE-associated genes.

Yu Qiao, Jian-Fei Xu, Lin Zheng et al. · bioRxiv · 0 citations