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Mos-Gen: A Generative Molecular Framework for Mosquito Insecticide Design

Experimental results fully validated the high-precision screening capability of the Mos-Gen framework, a motif-aware generative collaborative framework that couples the pretrained molecular representation model Uni-Mol with a variational autoencoder (VAE) specifically tailored for the design of disulfide-containing allicin derivatives as mosquito insecticides.

Lina Wang, Yaning Cui · 0 citations