Linde Meyaard

TAMing the tumor: targeting immune inhibitory receptors on tumor-associated macrophages in pediatric brain tumors – an emerging immunotherapy strategy

Abstract Brain tumors are the most common solid tumors in children. Despite recent advancements in cancer survival, the prognosis for high-grade pediatric brain tumors remains poor, with treatments resulting in severe long-term side effects. Over the last decade, immune checkpoint blockade (ICB) has emerged as a promis...