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Lindsay B. Volk

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Open access Aug 2026

Sex and base excision repair as key susceptibility factors for alkylation-induced mutations, toxicity and hepatic cancer

N-Nitrosodimethylamine (NDMA) is present in food, water, and drugs and is considered a probable human carcinogen by the International Agency for Research on Cancer. The mechanism of action of NDMA involves the generation of carcinogenic methyl lesions such as 3-methyladenine (3MeA) on DNA bases. Alkyladenine DNA Glycos...

Jennifer E. Kay, J. Corrigan, Lindsay B. Volk et al. · 0 citations

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