Author

Ling-Bin Meng

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Open access Nov 2026

Circulating Tumor DNA Clearance Is Associated with Response and Survival in Metastatic Urothelial Carcinoma Treated with First-Line Enfortumab Vedotin Plus Pembrolizumab

Background/Objectives: Enfortumab vedotin plus pembrolizumab (EV+pembro) is the standard first-line treatment for metastatic urothelial carcinoma (mUC), yet no validated on-treatment biomarker identifies patients deriving a durable benefit. We evaluated whether circulating tumor DNA (ctDNA) clearance is associated with...

Adam Khorasanchi, Sayan Mullick Chowdhury, E. Hong et al. · Cancers · 0 citations

Jul 2026

Abstract PR005: Conditional Reprogramming Enables Rapid Establishment of Patient-Derived Neuroendocrine Tumor Models for Functional Precision Oncology

The findings demonstrate that conditional reprogramming provides a robust and scalable approach to generate clinically relevant NET models, enabling functional precision oncology, biomarker discovery, and therapeutic optimization, and may facilitate rapid clinical decision-making and accelerate the development of targe...

Jenny Li, Akshay Sood, Debasish Sundi et al. · Cancer Research · 0 citations