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Open access Oct 2026

MPTP-Induced D1R-Dependent Dysregulation of Ventral Hippocampal Newborn Cell Pools and Associated Alterations in the Hypothalamic–Pituitary–Adrenal Axis

Objective: This study investigated how dopaminergic (DAergic) depletion-induced ventral hippocampal neurogenesis triggers hypothalamic–pituitary–adrenal (HPA) axis hyperactivity. Methods: Three-month-old male C57BL/6 mice were subjected to systemic 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) or ventral tegmenta...

Ting-Ting Di, Kai Zhang, Qian Ru et al. · 0 citations

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