Ferroptosis and nutrient-metabolic pathway genes in ovarian cancer: integrated bulk and single-cell analysis of Iron-metabolic programs, immune-marker enrichment, and prognosis
Ovarian cancer (OC), particularly high-grade serous ovarian carcinoma (HGSOC), remains a lethal gynecological malignancy characterized by frequent recurrence and treatment resistance. Ferroptosis is governed by nutrient-related metabolic processes involving iron handling, cystine–glutathione antioxidant defense, li...