Review
Open access
Jul 2026
Spasmolytic Polypeptide‐Expressing Metaplasia in Chronic Atrophic Gastritis and Its Role in the Progression From Gastritis to Gastric Cancer
This review summarizes current knowledge on cellular plasticity, lineage dynamics, and molecular mechanisms underlying SPEM formation and progression in CAG and focuses on recent advances in oxyntic atrophy, immune cell and inflammation, as well as oxidative stress in gastric epithelial remodeling.
Xin Quan, Ling-Long Ji, Tian He et al.
· Journal of Digestive Disease... · 0 citations