Plasma antioxidant enzyme imbalance in childhood- and adolescent-onset schizophrenia: clinical correlates and diagnostic utility.
Chronic oxidative stress (OS) is strongly implicated in the pathobiology of adult-onset schizophrenia, while contributions to childhood- and adolescent-onset schizophrenia (CAOS) have not been extensively investigated. Here we examined abnormalities in peripheral OS markers and associations with symptoms in a large CAO...