Ling-Yan Jiang

Host inflammation-derived citrate enhances Salmonella Typhimurium pathogenesis by fueling growth and activating virulence.

Salmonella enterica serovar Typhimurium (STm) infection triggers robust intestinal inflammatory responses during host colonization. Although host inflammatory responses typically function as defense mechanisms, STm subverts these processes by co-opting inflammation-derived metabolites to increase both bacterial prolife...