Author

Ling-Yu Wu

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Open access 2026

Evaluation of treatment for acute hexavalent chromium poisoning in human renal proximal tubular epithelial cells with 2,3-dimercapto-1-propanesulfonic acid (DMPS).

OBJECTIVES Chelating agents have been utilized in clinical settings to counteract various heavy metal poisonings, although there are currently no established medical guidelines supporting the use of the chelating agent 2,3-dimercapto-1-propanesulfonic acid (DMPS) for treating acute hexavalent chromium (Cr(VI)) poisonin...

I-Jeng Yeh, Hsin-Liang Liu, Chin-She Lin et al. · American journal of translat... · 0 citations

Open access Sep 2026

Association of the GLM7 composite metabolic index with gestational diabetes mellitus in early pregnancy: a secondary analysis of a Korean prospective pregnancy cohort

Background Surrogate indices such as the triglyceride-glucose (TyG) index are widely used to estimate insulin resistance (IR), yet their ability to discriminate incident gestational diabetes mellitus (GDM) in early gestation remains suboptimal. This study evaluated whether the previously developed composite metabolic i...

Qin-Fei Zhao, Wei-Quan Hu, Xu-Xiang Xi et al. · Frontiers in Nutrition · 0 citations

Open access Jul 2026

Single-cell and spatial transcriptomics map lung-adaptive metastasis programs through Exoc4, Cd36-vasculogenic mimicry, and Cxcr2 signaling in triple-negative breast cancer.

These results highlight novel prognostic markers and therapeutic vulnerabilities with translational potential for treating TNBC lung metastasis and establish Exoc4, the Hif-2α-Cd36 vasculogenic mimicry axis, Cxcrl1/2-Cxcr2 signaling, and Sftpc as critical mediators of metastatic adaptation.

Hsiao-Chen Lee, C. Kuo, Fang-Ming Chen et al. · Cell Death and Disease · 0 citations