Open access
Aug 2026
Pramipexole alleviates non-motor symptoms and autophagy-related protein abnormalities in a dual neurotoxin Parkinson's disease model.
PPX significantly improved NMS, reducing anxiety/depressive -like behavior and cognitive decline, alongside restoring motor function, and this therapeutic effect may be associated with altered expression of autophagy-related proteins.
Shimin Pang, Jingyue Liu, Linghui Sheng et al.
· Brain Research Bulletin · 0 citations