Open access
Jul 2026
Bufothionine inhibits colorectal cancer progression via the STAT3/p53/SLC7A11 signaling axis
Background Bufothionine, a major bioactive component of dried toad skin, has shown anti-tumor potential. However, its efficacy and underlying mechanisms in colorectal cancer (CRC) remain unclear. Objective This study aimed to investigate the therapeutic potential of bufothionine and its underlying mechanisms against CR...
Rui-Fang Xie, Nan Xiang, Guidan Zhou et al.
· Frontiers in Pharmacology · 0 citations