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Lingwei Gao

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Review Open access Aug 2026

The NRF2 signaling pathway in hepatocellular carcinoma: dual roles, epigenetic reprogramming, and therapeutic opportunities in metabolic vulnerability

Hepatocellular carcinoma (HCC) is a highly heterogeneous malignant tumor with a poor prognosis; its onset and progression are closely associated with persistent oxidative stress and metabolic reprogramming. Nuclear factor E2-related factor 2 (NRF2), as a key transcription factor regulating redox homeostasis, exerts a c...

Yue Wang, Lingwei Gao, Hao-Bo Yang et al. · 0 citations

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