Prevalence and Clinical Implications of Somatic and Germline EGFR Mutations in Patients with Non-Small-Cell Lung Cancer
Simple Summary Epidermal Growth Factor Receptor (EGFR) is frequently overexpressed or mutated in epithelial-derived tumors. In non-small-cell lung cancer (NSCLC), activating EGFR mutations in the cytoplasmic tyrosine kinase domain are important therapeutic targets. EGFR-targeted therapy was among the earliest successfu...