Review
Open access
Aug 2026
Immune response to DNA and RNA: structural insights, molecular mechanisms, and therapeutic targeting
Evidence is synthesized as a two-fate problem: whether an endogenous nucleic acid accumulates at these sensors to drive autoinflammation or is cleared by nucleases before detection is set by the balance between sensor engagement and clearance capacity.
Lintao Xia, Yi-Xi Wang, Xiu-Li Yan et al.
· Molecular Biomedicine · 0 citations