Aug 2026
KLHL1 suppresses triple-negative breast cancer progression by promoting M1 macrophage polarization via APOC2 degradation.
Findings reveal that activation of the KLHL1/APOC2 axis enhances M1 macrophage polarization and inhibits TNBC progression, providing novel insights into the immune regulatory mechanisms underlying TNBC development.
Zi-Ran He, Zhen-Hua Zhang, Li Ding et al.
· Biochimica et Biophysica Act... · 0 citations