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Author

Liuxin Yang

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Aug 2026

Bifunctional Ionophores for Cuproptosis Activation: Dual Targeting of Copper and Fe-S Protein Homeostasis.

Cellular resilience to therapy often arises from adaptive mechanisms that safeguard iron-sulfur (Fe-S) proteins. Here, we present a rational strategy to overcome such resilience by integrating two synergistic vulnerabilities, copper toxicity and Fe-S cluster homeostasis, into a single molecular scaffold. Inspired by a...

Liuxin Yang, Yiyu Cheng, Si Qin et al. · 0 citations

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