Author

Lixin Ren

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Open access Jul 2026

Reference Regulatory Element-Guided Gene Expression Analysis for Mechanistic Inference of Gene Regulatory Networks

Regulatory Elements Guided Analysis (REGA), an interpretable framework that uses reference Regulatory Element (RE) catalogs to infer transcription factor (TF)–RE–gene programs from gene expression data, enables scalable, interpretable GRN analysis across expression datasets.

Lixin Ren, Ishita Debnath, Zhana Duren · bioRxiv · 0 citations