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Open access Oct 2026

Biological characterization of the lytic Pseudomonas aeruginosa phage BUCT980 and its therapeutic efficacy in a murine lung infection model

ABSTRACT Pseudomonas aeruginosa is an important opportunistic pathogen whose increasing multidrug resistance limits conventional antimicrobial treatment options and underscores the need for alternative antibacterial strategies. In this study, we isolated and systematically characterized a novel lytic phage, BUCT980, an...

Xiao Yu, Jing-Wen Chen, Wei-Hua Zhang et al. · 0 citations
Review Open access Aug 2026

Modeling the lung‒brain axis in critical illness: Multifactorial crosstalk through organoids and organ‐on‐a‐chip system

Neurological sequelae, ranging from acute brain dysfunction (e.g., delirium) to long‐term cognitive impairment, are increasingly recognized as significant complications in survivors of critical care units, particularly in patients with lung injury caused by severe pulmonary inflammation mechanical ventilation. However,...

Wanyi Zhang, Tingfa Wang, Mengying Yao et al. · 1 citation

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