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Lizhen Cheng

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Open access Jul 2026

Blood transcriptomic signatures link β-amyloid deposition to molecular pathways across SCD, MCI, and dementia

Introduction Brain β-amyloid (Aβ) accumulation is a hallmark of Alzheimer’s disease, but noninvasive detection remains challenging. Blood transcriptomics may provide accessible biomarkers associated with Aβ pathology. Methods We integrated peripheral blood transcriptomic profiling and MRI-derived structural metrics fro...

Yijia Lin, Lizhen Cheng, Zhen Zhang et al. · 0 citations

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