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Li-Zhen Liang

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Sep 2026

Joint effects of per- and polyfluoroalkyl substances and heavy metals on dyslipidemia: Integrated epidemiological and bioinformatics analysis.

Exposure to per- and polyfluoroalkyl substances (PFAS) and heavy metals may be associated with dyslipidemia. However, evidence regarding the joint associations and potential interactions of these pollutants remains limited, and the biological pathways that might be relevant to these associations are not yet fully under...

Yuan-Yuan Fan, Li-Zi Lin, Muhammad Amjad et al. · 0 citations
Open access Sep 2026

Preconception heat exposure and risk of macrosomia: evidence from a nationwide birth cohort in China.

Extreme heat is an increasing concern for maternal and neonatal health, yet the relevance of heat exposure before conception remains insufficiently understood. Using a nationwide birth cohort of 233,842 mother-infant pairs in China, including 12,737 macrosomia cases, we examined associations of preconception and prenat...

Hong Zhu, Shen-Jing He, Wen-Ju Cai et al. · 0 citations
Sep 2026

F-53B drives placental inflammation via an IL1R1-mediated NLRP3 inflammasome activation: Evidence from epidemiology and a laboratory experiment.

Our prior work suggested that gestational exposure to chlorinated polyfluorinated ether sulfonates (F-53B) induces placental inflammation by activating the NLRP3 inflammasome, but the primary molecular target remains unclear. This study examined whether interleukin-1 receptor type 1 (IL1R1) served as a key target in F-...

Kun Zhao, Yun-Ting Zhang, Jian-Ping Cong et al. · 0 citations
Open access Aug 2026

Selenium predominance in heavy metal mixtures is associated with hyperuricemia in Chinese adults: the role of insulin resistance

Insulin resistance might be a crucial mediated pathway between Se and outcomes and three multi-pollutant models revealed positive associations between metal mixtures and SUA as well as HUA, with Se being the primary contributor.

Jing-Fu Lai, Ya-Qin Zhang, Yun-Ting Zhang et al. · 0 citations
Jul 2026

PM2.5-bound organophosphate esters and childhood attention-deficit hyperactivity disorder symptoms: A population-based study from China.

It is suggested that inhalation of OPE mixtures may be associated with adverse neurodevelopmental outcomes in children, highlighting a potential developmental window of susceptibility and raising public health concerns about airborne contaminants.

Chu Chu, Xuan Liu, Yan-xu Chen et al. · 0 citations

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