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Author

Logan T. Neel

1 paper indexed here

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Open access Nov 2026

Design, Synthesis, and Pharmacological Characterization of Novel Kappa Opioid Receptor Agonists via Isosteric Replacement Strategy for Inflammatory Pain

Pain management remains a critical challenge, with mu opioid receptor (MOR) agonists carrying significant risks of respiratory depression and addiction. Kappa opioid receptor (KOR) agonists offer a promising alternative, but centrally mediated adverse effects such as sedation and dysphoria limit their clinical utilit...

Ahmed M. Reda, Logan T. Neel, Celsey M. St. Onge et al. · 0 citations

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