Author

Long-Fei Dai

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Aug 2026

Non-Invasive Strategy for Gastric Cancer Detection: Integration of Cell-free DNA Fragmentomics and Protein Biomarkers.

Gastric cancer (GC) ranks as the fifth most common cancer worldwide, however, accurate and non-invasive diagnostic modalities for GC remain limited. Cell-free DNA (cfDNA) fragmentomics has emerged as a promising tool for cancer cell detection. Here we develop a gastric cancer detection model, named GaFraD model. The Ga...

Yue-qing Huang, Xue-Fei Xu, Nannan Jiang et al. · Cancer Letters · 0 citations

Open access Sep 2026

TGM2 Activates the ERK Signaling Pathway to Disrupt Intestinal Barrier Function and Aggravate Colitis.

BACKGROUND PANoptosis-related transcriptional programs may contribute to pediatric ulcerative colitis (UC), but the genes most consistently associated with disease activity and epithelial injury remain uncertain. METHODS Public transcriptomic cohorts were integrated with machine-learning feature selection, treatment-...

Hong-Fu Dai, Long-Fei Dai, Yu-Feng Xu et al. · Frontiers in Bioscience · 0 citations