Author

Long-Fei Han

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Open access Oct 2026

Construction of Recombinant PRV Expressing PRRSV Antigens and Evaluation of Their Protective Efficacy in Pigs Against Homologous Challenge

Background/Objectives: Porcine reproductive and respiratory syndrome virus (PRRSV) remains a major threat to the global swine industry, while the emergence of variant pseudorabies virus (PRV) strains has further complicated disease control in China. This study aimed to develop a PRV-based viral vector platform for PRRS...

Shang-Hui Wang, Yun-Fei Liu, Long-Fei Han et al. · Vaccines · 0 citations

Open access Aug 2026

Comparative Phenotypic Characterization of Five CRISPR/Cas9-Generated Gene-Disrupted Mutants of Pseudorabies Virus JM Strain

Simple Summary Pseudorabies virus (PRV) is an important swine pathogen that can also infect a broad range of non-porcine mammals. In this study, five PRV genes, UL21, UL24, UL50, UL56, and gG, were individually disrupted in the same PRV JM genetic background using CRISPR/Cas9, and the resulting viruses were comparative...

Long-Fei Han, Shang-Hui Wang, Zhao-Xia Zhang et al. · Veterinary Sciences · 0 citations