Liver fibrosis links chronic liver injury to cirrhosis, hepatic decompensation, and hepatocellular carcinoma (HCC), while current non-invasive tests mainly estimate fibrotic burden and incompletely capture active stromal biology. Fibroblast activation protein-α (FAPα), a cell-surface serine protease enriched in activat...
Peng An, Long-Long Wu, Rong Wang· Biomedicine & pharmacotherap...· 0 citations
Acute pancreatitis (AP) is a sterile inflammatory disease initiated by acinar cell stress and amplified through innate immune, vascular, and inter-organ responses, yet effective disease-modifying therapies remain unavailable. Although premature digestive enzyme activation, organelle stress, sterile inflammation, and mi...
Meng-Wei Chen, Peng An, Sheng-Long Jing et al.· Frontiers in Immunology· 0 citations
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