Oct 2026
CD74 accumulation in macrophages suppresses efferocytosis and exacerbates atherosclerosis by interfering with myosin II function.
Defective macrophage efferocytosis is a critical driver of the progression of inflammatory diseases such as atherosclerosis (AS), yet whether Cluster of Differentiation 74 (CD74) participates in this process remains unclear. In this study, using RAW264.7 macrophages as a model, we found that pharmacological inhibition...
Rong-Fang Chen, Jun-Qing Lin, Le-Ye Yan et al.
· Archives of Biochemistry and... · 0 citations