Open access
Oct 2026
AZD6738 reverses the LPS-induced corneal inflammatory transcriptional program through a conserved transcription factor network converging on NF-κB
AZD6738 reverses a substantial part of the LPS-induced corneal inflammatory transcriptome and suppresses an inflammatory TF program whose regulons are conserved in human bacterial keratitis, supporting ATR inhibition as an adjunct to antimicrobial therapy in bacterial keratitis.
Q. Ye, Kai Chen, Long-Xiang Huang et al.
· Frontiers in Medicine · 0 citations