Author

Long Zeng

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Open access Aug 2026

Large-FOV, dual-region, two-photon fluorescence lifetime imaging microscopy (LD-2P-FLIM) for multiparameter and quantitative brain function imaging

Significance Two-photon microscopy (TPM) is ideally suited for in vivo brain function imaging because of its high resolution and deep tissue penetration. However, conventional TPM is limited by a restricted field-of-view (FOV), an inherent trade-off between the imaging area and temporal resolution, and an insufficient...

Shi-Wei Ye, Yu-Feng Gao, Mengying Deng et al. · Proceedings of the National... · 0 citations

Open access Sep 2026

Central medial thalamic nucleus–targeted temporal interference stimulation promotes arousal: translational evidence from optimized preclinical models to patients with disorders of consciousness

Patients with disorders of consciousness (DoC) lack effective non-invasive neuromodulation therapies capable of targeting deep-brain arousal circuits. Temporal interference stimulation (TIS) offers potential for non-invasive deep brain targeting. However, its efficacy, optimal stimulation parameters, and underlyi...

Ze Wu, Long Zeng, An-Bo Zhang et al. · Journal of Translational Med... · 0 citations