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Long-Fei Li

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Aug 2026

Design, synthesis, and antifungal activity study of N-substituted phenyl pyrazole containing amides.

BACKGROUND Plant pathogenic fungi pose a serious threat to global crop productivity. Succinate dehydrogenase inhibitors (SDHIs) exhibit superior curative activity, longer residual efficacy, and lower mammalian toxicity compared to other fungicides, making them the most studied fungicide class. RESULTS A series of N-s...

Wei Zhang, Ren‐ming Yu, Yi Wang et al. · 0 citations
Open access Aug 2026

DASH: A Pocket-Aware and Objective-Aware Framework for Million-Scale Structure-Based Molecular Generation

DASH is presented, a pocket-aware and objective-aware framework for converting protein-conditioned diffusion outputs into property-tagged molecular libraries for computational prioritization and can adapt inference effort across pockets, rerank generated libraries under different design objectives, and produce standard...

Baohua Zhang, Huangchao Xu, Xiaoning Wang et al. · 0 citations

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