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Author

Longxiao Zhang

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Open access Sep 2026

Genetic Prioritization of Plasma Proteins Across Dementia Subtypes: A Proteome-Wide Mendelian Randomization and Bayesian Colocalization Analysis

Dementia is clinically and biologically heterogeneous, and genetically supported plasma protein associations across dementia subtypes remain incompletely characterized. We aimed to genetically prioritize plasma proteins associated with overall dementia and major dementia subtypes using proteome-wide Mendelian randomiza...

Xin-Yang Yan, Long-Xiao Zhang, Jia-Xi Li et al. · 0 citations
Jul 2026

Integrating Large-Scale Bulk and Single-Cell RNA Sequencing with Machine Learning: Unveiling the Cytokine Landscape of Glioblastoma and Constructing a Prognostic Feature Model.

INTRODUCTION Cytokines play an important role in modulating the tumor microenvironment (TME) in glioblastoma multiforme (GBM). However, little work has focused on developing a prognostic model for GBM using cytokine signatures. METHODS Herein, we combined several GBM datasets, such as GSE163120, TCGA-GBM, CGGA-693, C...

Longxiao Zhang, Xinyang Yan, Yunfei Zhou et al. · 0 citations

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