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Author

Lu Chai

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Open access Oct 2026

DeCTCF: Decoding CTCF binding sequences by leveraging predicted epigenomic features

CTCF is a key architectural protein with diverse roles in genome organization and gene regulation, yet how it achieves these roles in different contexts remains unclear. Pretrained sequence-based models such as Sei provide predicted epigenomic features that can be used in downstream analyses of regulatory elements. Her...

Lu Chai, Jie Gao, Ting Guo et al. · 0 citations
Open access Jul 2026

High-throughput sequencing and analysis of target genes uncover microRNA-mediated responses to low-temperature stress in Medicago falcata.

The authors' results identified candidate cold-responsive miRNAs in M. falcata and predicted their target genes involved in diverse biological processes and showed that the miR408-5p-MfbZIP10 module plays a crucial regulatory role in low-temperature adaptation.

Mei Yang, Lu Chai, Yuxuan Liu et al. · 0 citations

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