Author

Lu-Jun Chen

2 papers indexed here

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Review Open access Oct 2026

Emerging roles and mechanistic insights of ASRGL1 in tumorigenesis and cancer progression.

Asparaginase and isoaspartyl peptidase 1 (ASRGL1), also known as ALP, CRASH, hASNase3, is a protein encoded by the ASRGL1 gene located at chromosome 11q12.3 in humans. It belongs to the N-terminal nucleophilic (Ntn) hydrolase superfamily and catalyzes the hydrolysis of L-asparagine and isoaspartyl dipeptides, thereby p...

H. Zeng, Ze-Kang Li, Ren-Hao Geng et al. · Frontiers in Cell and Develo... · 0 citations

Review Open access Sep 2026

Recent Advances in Chronic Myeloid Leukaemia (CML): Emerging Molecular and Immunotherapeutic Targets.

The pivotal role of LSCs in disease progression and relapse is highlighted, potential molecular and epigenetic regulators as new targets for intervention are evaluated, and the development of combination treatment strategies to improve TFR rates and move towards curative outcomes is supported.

Jing-Yi Dai, Pan-Pan Zheng, Jian Liu et al. · Frontiers in Bioscience · 0 citations