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Review Open access Oct 2026

Comparative efficacy of gut microbiota-targeted therapies for motor and non-motor symptoms in Parkinson's disease: a systematic review and network meta-analysis

Gut dysbiosis may contribute to Parkinson's disease (PD) through the microbiota-gut-brain axis. Probiotics, synbiotics, and fecal microbiota transplantation (FMT) have been studied as potential treatments, but their comparative effects remain uncertain. We searched trial registries and electronic databases f...

Xiao-Yuan Yang, Yuan-Ping Li, Qing-Hong Hu et al. · 0 citations
Open access Sep 2026

Feline Milk-Derived Lactiplantibacillus plantarum MNN and Galacto-Oligosaccharides Ameliorate Stress-Related Behavioral Abnormalities and Alter Tryptophan Metabolism in CSDS Mice

Chronic stress is a critical predisposing factor for neuropsychiatric and metabolic disorders, profoundly affecting both physical health and behavioral performance. Stress induces gut microbiota dysbiosis and disrupts tryptophan metabolism, notably via the kynurenine (KYN) and 5-hydroxytryptamine (5-HT) pathways. Targe...

Xue Wang, Xin-Yu Gong, Shao-Hui Lang et al. · 0 citations

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