CAR T Cell Therapy in Lung Cancer: Overcoming Tumor Microenvironment-Mediated Barriers
Chimeric antigen receptor (CAR) T cell therapy has achieved remarkable clinical success in hematological malignancies. However, its efficacy in solid tumors such as lung cancer remains constrained by the immunosuppressive tumor microenvironment (TME). Aberrant vascular architecture and dense stroma constitute major phy...